BIOL 230 Lecture Guide - NK Cell Killing a Cell Not Expressing MHC-I Molecules

Fig. 4: NK Cell Interacting with a Virus-Infected Cell or a Mutant Cell
Not Expressing MHC-I Molecules

Viruses and malignant transformation can sometimes interfere with the ability of the infected cell or tumor cell to express MHC-I molecules. Without the signal from the killer-inhibitory receptor, the kill signal from the killer-activating signal is not overridden and the NK cell kills the cell to which it has bound.

Illustration of an NK Cell Interacting with a Virus-Infected Cell or a Mutant Cell Not Expressing MHC-I Molecules.jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser

Fig. 4: NK Cell Interacting with a Virus-Infected Cell or a Mutant Cell Not Expressing MHC-I Molecules

Fig. 4: NK Cell Interacting with a Virus-Infected Cell or a Mutant Cell
Not Expressing MHC-I Molecules