The Adaptive Immune System: Antigens

Self Quiz for II. Antigens and Epitopes

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. Match the following:

_____ A substance that reacts with antibody molecules and antigen receptors on lymphocytes. (ans)

_____ An antigen that is recognized by the body as non-self and stimulates an adaptive immune response. (ans)

_____ The actual portions or fragments of an antigen that react with receptors on B-lymphocytes and T-lymphocytes as well as with free antibody molecules. (ans)

_____ An antibody molecule composed of 4 glycoprotein chains whose Fc portion is anchored to the membrane of certain lymphocytes; able to recognize epitopes on protein and polysaccharide antigens. (ans)

_____ A molecule composed of 2 glycoprotein chains anchored to the membrane of certain lymphocytes; able to recognize peptide epitopes from protein antigens presented by the body's own cells by way of MHC molecules. (ans)

_____ Antigens are proteins found within the cytosol of human cells such as viral proteins, proteins from intracellular bacteria, and tumor antigens. (ans)

_____ An organism’s own antigens (self-antigens) that stimulate an autoimmune reaction. (ans)

_____ Antigens that enter from outside the body, such as bacteria, fungi, protozoa, and free viruses. (ans)

a. B-cell receptor

b. T-cell receptor

c. immunogen

d. hapten

e. epitope

f. antigen

g. autoantigens

h. endogenous antigens

i. exogenous antigens.

2. Briefly describe how the body recognizes an antigen as foreign. (ans)

3. In terms of infectious diseases, describe 2 categories of microbial materials that may act as an antigen.

a. (ans)

b. (ans)

4. Describe 3 groups of noninfectious materials that may act as an antigen.

a. (ans)

b. (ans)

c. (ans)

5. Multiple Choice (ans)

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