BIOL 230 Lecture Guide - Diapedesis During Inflammation

Fig. 12: Diapedesis During Inflammation

Integrins on the surface of the leukocyte bind to adhesion molecules on the inner surface of the vascular endothelial cells. The leukocytes flatten out and squeeze between the endothelial cells to leave the blood vessels and enter the tissue. The increased capillary permeability also allows plasma to enter the tissue.