Fig. 11: Activation of a B-lymphocyte by way of LPS Binding to Toll-like Receptors

TI-1 antigens include lipopolysaccharide (LPS) from the outer membrane of the gram-negative cell wall and bacterial nucleic acid. These antigens activate B-lymphocytes by binding to their specific toll-like receptors rather than to B-cell receptors. Binding of LPS to its toll-like receptor activates chemical signals that lead to transcription of antibody and cytokine genes.

 

Illustration of Activation of a B-lymphocyte by way of LPS Binding to Toll-like Receptors .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html..

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Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser