Most T-cell receptors are composed of two polypeptide chains, an alpha (α) chain and a beta (β) chain. The variable domains of the α and β chains (red) provide specificity for binding a peptide bound to a MHC molecule. The terminus of the constant domains (purple) anchors the receptor to the cytoplasmic membrane of the T-lymphocyte. (S-S = disulfide bond)
Last updated: Feb., 2021
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Gary Kaiser