All nucleated cells produce MHC-I molecules. MHC-I molecules bind peptide epitopes of antigens found within our cells. Peptide epitopes bound to MHC-I molecules are recognized by TCRs and CD8 molecules on the surfaces of naive T8-lymphocytes and on cytotoxic T-lymphocytes (CTLs).
Why is it important that all nucleated cells in our body are able to produce MHC-I molecules?