Self Quiz for The Adaptive Immune System: Primary Immunodeficiency

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. Match the following:

_____ Rare but severe primary immunodeficiencies occuring as the result of a rare recessive genetic defect in the immune responses that involves the development of B-lymphocytes, T-lymphocytes, or both and results in multiple, recurrent infections during infancy. (ans)

_____ Common, less severe primary immunodeficiencies involving just one or more of the huge number of genes involved in the immune responses. They involve the decreased ability to combat just a single type of infection or a narrow range of infections and relate to an individual’s own unique genetics. (ans)

_____ There may be greatly decreased humoral immunity but cell-mediated immunity remains normal. X-linked agammaglobulinemia and selective IgA deficiency are examples. May be treated with artificially-acquired passive immunization. (ans)

_____ Primary immunodeficiencies that affect both humoral immunity and cell-mediated immunity. There is a defect in both B-lymphocytes and T-lymphocytes, or just T-lymphocytes in which case the humoral deficiency is due to the lack of T4-helper lymphocytes. (ans)

a. B-lymphocyte disorder

b. combined B-lymphocyte and T-lymphocyte disorder

c. novel primary immunodeficiency

d. conventional primary immunodeficiency

2. Infants born with a nonfunctional thymus develop frequent and severe infections. Explain. (ans)


Gary E. Kaiser, Ph.D.
Professor of Microbiology
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a
Creative Commons Attribution 4.0 International License.
Based on a work The Grapes of Staph at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Creative Commons License

Last updated: Feb., 2020
Please send comments and inquiries to Dr. Gary Kaiser